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About Tramadol 50Mg Tramadol is a synthetic opioid analgesic for managing and preventing mild to moderate pain. It works in the brain to change how your body feels and responds to pain. Tramadol belongs to the opioid analgesics group of drugs and pain relievers for adults to treat moderate to severe pain. Buy Tramadol 50Mg Online. It binds to the mu-opioid brain and spinal cord receptors, reducing pain sensation. Tramadol comes in both immediate and extended-release formulations. The immediate-release formulation is typically used for acute pain relief, whereas the extended-release formulation is used to manage chronic pain.