Many women with unsuccessful IVF cycles will succeed on their second or third attempt. Not all problems affecting IVF efficiency can be solved, but some problems can be solved to improve the chances of pregnancy in the next cycle. Age The age of the female partner is the most important predictor of IVF success. As women get older, their eggs become older, fewer eggs are produced, and the quality of the eggs decreases. It starts in your thirties and accelerates after you reach the age of 37. According to the survey, the chance of live birth from an IVF cycle using fresh non-donor eggs is about 32% for a 35-year-old woman but only 12% for a 41- or 42-year-old woman. Embryos Quality Another reason for IVF cycle failure is poor embryo production. Usually, chromosomal or genetic defects prevent the embryo from implanting and maturing. Older eggs are more likely to produce poor-quality embryos. Poor-quality embryos can also be the result of sperm defects and morphological problems. Ovarian Reaction Many eggs are produced by the ovaries in response to fertility medication, which is essential for successful IVF. Due to hormonal disturbances, which can occur in women with normal reserves in some cycles or even when there are fewer eggs in their ovaries than expected, in some cases, women cannot produce more than one egg. If you are over 37, you are more likely to have a subpar response if you have high FSH (follicle-stimulating hormone) or low AMH (anti-Müllerian hormone) levels. How to prepare for the next cycle? Before your next visit, your fertility specialist will carefully review your cycle history, including problems with ovarian stimulation, egg quality or quantity, embryo formation, or embryo transfer to your uterus. Related blog: 8 Proven Ways To Maximize Your IVF Success Rates If you experience problems with ovarian stimulation or egg production, your doctor may suggest changing the medication used in the next stimulation procedure. If the eggs and embryos are healthy, a second IVF cycle can be successful. Some doctors recommend hysteroscopy to help regenerate the endometrium and thus increase the chances of implantation in the next cycle. If a strong genetic cause is suspected or you have a history of repeated miscarriages, your doctor may recommend preimplantation genetic screening (PGS) to screen embryos in your next IVF cycle. PGS is performed before implantation. This procedure involves removing a biopsy from the fetus and examining the cells for the number of chromosomes. This allows experts to select healthy embryos that are free of genetic abnormalities. If the eggs and embryos are found to be healthy and no other problems are found, your second IVF cycle can have the expected results.
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